The present invention relates to a pump cassette. The pump cassette includes a housing including at least one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump 820 within the housing. A pressure pump pumps fluid from the fluid inlet line to the fluid outlet line. Also included are a hollow spike 902 on the housing and at least one metering pump 830 . A metering pump 830 is fluidly connected to the hollow spike 902 on the housing and a metering pump fluid line. A metering pump fluid line is fluidly connected to the fluid outlet line.
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