2 USE OF DIANHYDROGALACTITOL AND ANALOGS AND DERIVATIVES THEREOF TO TREAT RECURRENT MALIGNANT GLIOMA OR PROGRESSIVE SECONDARY BRIAN TUMOR

摘要

Methods and compositions suitable for the treatment of malignancies such as recurrent gliomas and advanced secondary brain tumors are disclosed. These methods use hexitol derivatives such as dianhydrogalactitol, a derivative or analog of dianhydrogalactitol, diacetyldianhydrogalactitol, or a derivative or analog of diacetyldianhydrogalactitol. The composition may include such a hexitol derivative.