Composition for improving preventing or treating Neuropsychiatry disorders diseases comprising Fraction of agarwood extracts

摘要

The present invention relates to a composition for preventing, improving, or treating brain neuropsychiatric disorders, comprising a fraction of an extract of aloes agarula as an active ingredient. The composition comprising the fraction of the extract according to the present invention as an active ingredient was confirmed to have a significant effect of 95% or more reliability in a non-clinical experiment, an animal experiment using rodents, and was also clinically reported for depression and anxiety. The improvement effect such as reduction of nitric oxide (NO), NLRP3 inflammasome, ASC and IL-1β, which is a pharmacological mechanism related to neuropsychiatric disorders as the main symptom, was verified and reduced significantly with a reliability of 95% or more. Identified, it can be usefully used as a composition for preventing, improving or treating brain neuropsychiatric disorders.