首页> 外国专利> Use of TCTP as biomarker for predicting efficacy, prognosis of immunotherapy or resistance thereto, and target of immunotherapy for enhancing efficacy

Use of TCTP as biomarker for predicting efficacy, prognosis of immunotherapy or resistance thereto, and target of immunotherapy for enhancing efficacy

机译:TCTP作为生物标记物用于预测免疫治疗的疗效、预后或耐药性,以及提高疗效的免疫治疗靶点

摘要

The present invention relates to biomarkers for predicting the efficacy, prognosis, or resistance of immunotherapy, and the use of TCTP as a target for enhancing the efficacy of immunotherapy. When using the biomarkers (TCTP, EGFR, AKT, MCL1, and/or CXCL10) of the present invention, it is possible to predict resistance and prognosis to immunotherapy, select a therapy that provides a therapeutic advantage, and to be resistant to immunotherapy It can be usefully used to treat cancer or tumors with .
机译:本发明涉及用于预测免疫治疗的疗效、预后或耐药性的生物标记物,以及将TCTP用作增强免疫治疗疗效的靶点的用途。当使用本发明的生物标记物(TCTP、EGFR、AKT、MCL1和/或CXCL10)时,可以预测对免疫治疗的耐药性和预后,选择具有治疗优势的治疗,并对其可有效用于治疗癌症或肿瘤的免疫治疗产生耐药性。

著录项

  • 公开/公告号KR20220067657A

    专利类型

  • 公开/公告日2022-05-25

    原文格式PDF

  • 申请/专利权人 고려대학교 산학협력단;

    申请/专利号KR1020200154101

  • 发明设计人 김태우;이효정;

    申请日2020-11-17

  • 分类号C12Q1/6886;A61K31/137;A61K31/357;A61K31/436;A61K31/5415;A61K45/06;A61P35;C12Q1/6809;G01N33/574;G01N33/68;

  • 国家 KR

  • 入库时间 2022-08-25 01:13:20

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