A COMPOSITION COMPRISING THE COMPOUNDS ISOLATED FROM AN EXTRACT OF AGRIMONIA COREANA NAKAI AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING IMMUNE-INVOLVED DISEASE AND THE USE THEREOF

摘要

The present invention relates to composition comprising the compounds isolated from the extract of Agrimonia coreana NAKAI, a Korean native plant, to treat and prevent immune involved diseases and the inventive compounds isolated from the extract of Agrimonia coreana NAKAI, a Korean native plant, showed potent immune-modulating activity through various tests such inhibition effect on T cell proliferation (Experimental Example 1), inhibition effect on ORAI1 ion channel regulating calcium signaling in cell (Experimental Example 2) and therefore the compounds can be useful in treating or inhibiting effect on various immune involved diseases.