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COMPUTATIONAL CARDIAC DEPOLARIZATION AND REPOLARIZATION SIMULATION LIBRARY MAPPING FOR NON-INVASIVE ARRHYTHMIA RISK STRATIFICATION
COMPUTATIONAL CARDIAC DEPOLARIZATION AND REPOLARIZATION SIMULATION LIBRARY MAPPING FOR NON-INVASIVE ARRHYTHMIA RISK STRATIFICATION
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机译:计算心脏去极化和复极模拟库映射用于无创性心律失常风险分层
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摘要
A non-invasive method for cardiac arrhythmia risk stratification may include identifying, based at least on an electrical recording of a patient, a cardiac depolarization simulation and a cardiac repolarization simulation corresponding to an electrical recording of a patient. One or more regions of increased spatial repolarization gradient in which a first area of a myocardium of the patient exhibits a first repolarization rate that differs from a second repolarization rate of a second area of the myocardium by an amount then divided by the spatial distance between the two regions, by a threshold value may be determined based on the cardiac depolarization simulation and the cardiac repolarization simulation. A risk of cardiac arrhythmia for the patient may be determined based a magnitude of the increased spatial repolarization gradient. Moreover, a treatment plan for the patient may be determined based on the magnitude and/or location of the increased spatial repolarization gradient.
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