Protein Transducing Domain, Fusion Compound containing the Protein transducing Domain, and Pharmaceutical Composition containing the Fusion Compound

摘要

Problems to be solved by the present invention: To provide a more efficient novel protein transport domain and fusion compound. Means to solve the problem: As a result of selecting and testing numerous candidate peptides in order to solve the above problem, the present inventors found that a GK3 peptide consisting of 18 amino acids and a modified sequence in which several sequences are substituted, added or deleted using this as a basic sequence It was found that by binding to polymers such as proteins, the polymers can smoothly penetrate into living bodies such as cells, tissues, and blood. A fusion compound, oligonucleotide or vector using the same can be applied as a pharmaceutical composition for preventing or treating diseases.