RECOMBINANT FUSION PROTEINS COMPRISING INTERLEUKIN- 18-BINDING PROTEIN AND ANTIGEN BINDING FRAGMENT TO SERUM ALBUMIN, AND COMPOSITIONS AND USES THEREOF

摘要

Provided are recombinant fusion proteins comprising an interleukin- 18-binding protein and an antigen binding fragment against serum albumin and uses thereof. The recombinant fusion proteins have an improved administration cycle due to an increase in the half-life in the body. Further, the recombinant fusion proteins have low immunogenicity and do not cause side effects in vivo, and therefore, can be effectively used for the treatment of various cancers and immune diseases and conditions.