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A skin wound healing promoting composition for skin application, a method for producing the same, and a wound dressing.

机译:一种用于皮肤应用的促进皮肤伤口愈合的组合物,其制备方法,以及伤口敷料。

摘要

To provide skin-wound healing promoting compositions for skin application that contain lactic acid bacteria as an active ingredient, to provide methods for producing the same, and to provide wound dressings.SOLUTION: A skin-wound healing promoting composition for skin application contains as an active ingredient lactic acid bacterial powder having a median particle diameter of 1.0 μm or less measured by a wet type laser diffraction scattering method. The skin-wound healing promoting composition is produced by preparing a microbial cell concentrated liquid containing lactic acid bacteria so that the content of lactic acid bacteria is 0.01 mass% or more and less than 20 mass% in terms of dry bacterial cells in the concentrated liquid; adding a soluble excipient into the microbial cell concentrated liquid so as to be 12 mass% or more based on a final dry concentration; and pulverizing and dispersing the microbial cell concentrated liquid to which the soluble excipient is added, subsequently drying and powdering. A wound-dressing contains the above skin-wound healing promoting composition.SELECTED DRAWING: Figure 7
机译:本发明提供含有乳酸菌作为活性成分的用于皮肤应用的促进皮肤伤口愈合的组合物,提供生产该组合物的方法,以及提供伤口敷料。解决方案:一种用于皮肤应用的促进皮肤伤口愈合的组合物包含作为活性成分的乳酸菌粉末,其中值粒径为1.0μm或更小,通过湿式激光衍射散射法测量。皮肤伤口愈合促进组合物是通过制备含有乳酸菌的微生物细胞浓缩液来制备的,以浓缩液中的干细菌细胞计,乳酸菌的含量为0.01质量%或以上且小于20质量%;向微生物细胞浓缩液中添加可溶性赋形剂,以最终干浓度为12质量%或更高;以及粉碎和分散添加可溶性赋形剂的微生物细胞浓缩液,随后干燥和粉状。伤口敷料包含上述促进皮肤伤口愈合的组合物。所选图形:图7

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