METHOD FOR DETERMINING WHETHER A CELL SHOWN IN A NUCLEAR FLUORESCENCE IMAGE ACQUIRED THROUGH CONFOCAL MICROSCOPE IS A DISEASED CELL, IN PARTICULAR A TUMOROUS CELL

摘要

The present invention for determining whether a cell (C) shown in a nuclear fluorescence image acquired through a confocal microscope is a diseased cell, in particular a tumorous cell. Said method is based on the application of a discrete Wavelet transform to a reference matrix associated with a reference image (IREF) of the nucleus (C) of the cell, obtained by inserting a segmented image of said nucleus (C) on a background of a predetermined colour, to obtain four further matrixes, and on the generation of a respective Co-occurrence matrix for each further statistical function which characterize the nucleus (C) of said cell and are calculated starting from each Co-occurrence matrix, wherein said results are provided as input to a predetermined neural network (NN). The present invention relates also for determining whether a cell shown in a nuclear fluorescence image acquired through confocal microscope is a diseased cell, in particular a tumorous cell.