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METHOD AND APPARATUS TO MEASURE BONE HEMODYNAMICS AND DISCRIMINATE HEALTHY FROM DISEASED BONE, AND OPEN REDUCTION INTERNAL FIXATION IMPLANT WITH INTEGRATED OPTICAL SENSORS
METHOD AND APPARATUS TO MEASURE BONE HEMODYNAMICS AND DISCRIMINATE HEALTHY FROM DISEASED BONE, AND OPEN REDUCTION INTERNAL FIXATION IMPLANT WITH INTEGRATED OPTICAL SENSORS
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机译:测量骨血流动力学并区分健康和患病骨的方法和装置,以及具有集成光学传感器的切开复位内固定植入物
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摘要
An ORIF implant has an electronics module with a stimulus light and optical sensors for sensing fluorescent emissions coupled to a near-field digital radio. The implant is used with a near-field radio to receive a sequence of fluorescent emissions readings from the implant into a processor that fits the sequence of readings to a bone-specific kinetic model that is a superposition of a plug flow model of periosteal perfusion and a two-compartment model of endosteal perfusion of perfusion of bone. A system for use during ORIF surgery has an injector for fluorescent dye, a camera to send a sequence of images of fluorescent emissions from fluorescent dye in a bone of a subject to an image processor when the bone is illuminated with a stimulus light, the processor configured to fit the sequence of images to a model of perfusion of bone.
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