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METHOD OF EVALUATING PRE-CANCEROUS OR CANCEROUS LESIONS FOR ORAL CANCER
METHOD OF EVALUATING PRE-CANCEROUS OR CANCEROUS LESIONS FOR ORAL CANCER
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机译:口腔癌癌前病变或癌性病变的评估方法
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摘要
A method of collecting oral mucosal cells from a patient and evaluating the oral mucosal cells for oral squamous cell carcinoma predisposition in the patient includes collecting a sample of chewing gum from a patient that had chewed the chewing gum for a minimum of about 5 minutes up to about 30 minutes. The chewing gum includes a molecular adherent targeted towards oral mucosal cells with oral squamous cell carcinoma predisposition. A polymerase chain reaction (PCR) is performed on a DNA template prepared from the chewed chewing gum using oligonucleotide primers that are selected to amplify nucleic acids that screen for genomic sequence variations seen in genes that are indicative of oral squamous cell carcinoma predisposition in the patient.
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