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USE OF P44 AS MARKER FOR DIAGNOSING ANAPLASMOSIS

机译:P44作为无浆体病诊断标志物的应用

摘要

A novel use of P44 as a marker for predicting or diagnosing anaplasmosis is disclosed. A diagnostic composition for anaplasmosis containing a P44 gene, a primer set or probe for detecting Anaplasma phagocytophilum, a kit for diagnosing anaplasmosis, and a method for providing information to diagnose infection with Anaplasma phagocytophilum are also disclosed. P44, which is a novel biomarker for diagnosing anaplasmosis, is a multi-copy gene and exists in a large number of copies in the Anaplasma phagocytophilum genome, thus having the effect of detecting Anaplasma phagocytophilum infection at high sensitivity using only a small amount of DNA compared to conventional diagnostic marker genes. In addition, the primer set or probe for detecting and amplifying P44 is capable of providing rapid and easy detection of anaplasmosis with high specificity and sensitivity, making it appropriate for early detection of anaplasmosis.
机译:公开了P44作为预测或诊断无浆体病的标记物的新用途。还公开了含有P44基因的无浆体病诊断组合物、用于检测无浆体吞噬细胞的引物组或探针、用于诊断无浆体病的试剂盒以及用于提供诊断无浆体吞噬细胞感染信息的方法。P44是诊断无浆体病的一种新型生物标志物,是一个多拷贝基因,在无浆体吞噬细胞基因组中存在大量拷贝,因此与常规诊断标志基因相比,仅使用少量DNA即可高灵敏度检测无浆体吞噬细胞感染。此外,用于检测和扩增P44的引物组或探针能够快速、简便地检测无浆体病,具有高度的特异性和敏感性,适合无浆体病的早期检测。

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