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EXHALATION-BASED METHOD AND SYSTEM FOR DIAGNOSIS OF LUNGE CANCER

机译:基于呼气的肺癌诊断方法和系统

摘要

The present disclosure relates to exhalation-based lung cancer diagnosis method and system. The method may include: a step of preparing a surface-enhanced Raman spectroscopy (SERS) substrate; a step of eluting volatile organic compounds (VOCs) included in each of a plurality of cells, supplying each of the cellular VOC eluates to the SERS substrate and then measuring each of cellular SERS signals; a step of learning the signal pattern of each cell by applying deep learning to each of the cellular SERS signals; a step of collecting a patient's exhaled gas and liquefying the same using silicone oil, supplying the liquefied patient's exhaled gas to the SERS substrate and measuring an exhalation SERS signal, and then identifying the signal pattern of the exhaled gas by analyzing the exhalation SERS signal through the deep learning resu and a step of comparing and analyzing the signal pattern of the each of the cellular SERS signals and the signal pattern of the exhalation SERS signal, thereby identifying the cellular SERS signal having the highest similarity to the exhalation SERS signal, and confirming and notifying whether a lung cancer cell is present or not on the basis thereof.
机译:本公开涉及基于呼气的肺癌诊断方法和系统。该方法可以包括:制备表面增强拉曼光谱(SERS)衬底的步骤;将包括在多个细胞中的每种细胞中的挥发性有机化合物(VOC)的步骤,将每个蜂窝VOC洗脱在SERS基板中,然后测量每个细胞SERS信号;通过向每个蜂窝SERS信号应用深度学习来学习每个单元的信号模式的步骤;使用硅油收集患者的呼出气体和液化相同的步骤,将液化患者的呼出气体供应到SERS基板并测量呼气SERS信号,然后通过分析呼气信号信号来识别呼出气体的信号模式深度学习结果;以及比较和分析每个蜂窝SERS信号的信号模式的步骤和呼气SERS信号的信号图案,从而识别具有与呼气SERS信号的最高相似性的蜂窝SERS信号,并确认并通知吗?肺癌细胞存在于其基础上。

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