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METHODS OF OPTIMISING EXPRESSION AND DELIVERY OF MITOCHONDRIAL PROTEINS
METHODS OF OPTIMISING EXPRESSION AND DELIVERY OF MITOCHONDRIAL PROTEINS
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机译:优化线粒体蛋白的表达和递送的方法
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摘要
The invention relates to methods for the simultaneous expression and delivery to mitochondria of two or more proteins using a single expression vector. Also described are the expression vectors and host cells comprising the vectors. Where the proteins are genome editing reagents, the invention also relates to the use of the expression vectors to alter levels of mitochondrial heteroplasmy and treat mitochondrial disorders.
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