TREATMENT OF INCREASED LIPID LEVELS WITH STEROL REGULATORY ELEMENT BINDING TRANSCRIPTION FACTOR 1 (SREBF1) INHIBITORS

摘要

The present disclosure provides methods of treating subjects having increased lipid levels, methods of identifying subjects having an increased risk of developing an increased lipid level, methods of detecting human Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) variant nucleic acid molecules and variant polypeptides, and SREBF1 variant nucleic acid molecules and variant polypeptides.