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SYNTHETIC METHODS FOR PREPARATION OF 4-(2-CHLORO-4-METHOXY-5- METHYLPHENYL)-V-(LS)-2-CYCLOPROPYL-L-(3-FLUORO-4-METHYLPHENYL)ETHYL-5-METHYL-V-PROP-2-YNYL-L,3-THIAZOL-2-AMINE
SYNTHETIC METHODS FOR PREPARATION OF 4-(2-CHLORO-4-METHOXY-5- METHYLPHENYL)-V-(LS)-2-CYCLOPROPYL-L-(3-FLUORO-4-METHYLPHENYL)ETHYL-5-METHYL-V-PROP-2-YNYL-L,3-THIAZOL-2-AMINE
The present disclosure relates to the fields of chemistry and medicine, more particularly to processes for making 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2 -cyclopropyl-1-(3 -fluoro-4-methylphenyl)ethyl]-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine (Compound 1), pharmaceutically acceptable salts, and crystalline forms thereof, for the treatment of congenital adrenal hyperplasia (CAH).
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