SURFACE EXPRESSION VECTOR USING TWO KINDS OF PROMOTERS DERIVED FROM LACTOBACILLUS CASEI FOR CONCURRENTLY EXPRESSING TWO TARGET PROTEINS AND METHOD FOR EXPRESSING PROTEINS ON MICROBIAL SURFACE BY USING SAME

摘要

The present invention relates to a vector capable of co-expressing two different target proteins on the microbial surface using two promoters derived from Lactobacillus, and a method of expressing target proteins on the microbial surface using the vector. The vector containing foreign genes inserted therein is transformed into a microorganism, and allows different foreign proteins to be stably expressed on the surface of the microorganism. Furthermore, the present invention relates to a surface expression vector containing the gene pgsA encoding a poly-gamma-glutamate synthetase complex, and a method of expressing a target protein on the microbial surface using the vector. The vector containing foreign genes inserted therein is transformed into a microorganism, and allows the foreign proteins to be stably expressed on the surface of the microorganism.