Process for the preparation of ethyl 3-amino-1-(3R,4S)-4-cyanotetrahydropyran-3-ylpyrazole-4-carboxylate via chiral separation of a racemic mixture

摘要

Ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate and ethyl 3-amino-1-[(3S,4R)-4 -ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran- from racemic mixture (V) of cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate- A method for chiral separation of 3-yl]pyrazole-4-carboxylate (VI).