Urinary exosome-derived biomarkers for diagnosis or prognosis of T cell-mediated rejection in kidney allografts

摘要

The present invention relates to a biomarker for diagnosing non-invasive kidney transplant rejection and its use, and specifically, any one or more proteins selected from the group consisting of MGAM, SLC6A19, ACY3 and SLC5A10 or a gene encoding the same. Biomarker compositions and kits for diagnosing rejection or predicting the prognosis of kidney transplant rejection, a method of providing information necessary for diagnosing kidney transplant rejection or predicting the prognosis using the marker composition, providing information necessary for determining a treatment policy for kidney transplant rejection It relates to a method and a screening method for a therapeutic agent for rejection of a kidney transplant.