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Method or system for identifying mutations that cause the phenotype of interest in a test sample
Method or system for identifying mutations that cause the phenotype of interest in a test sample
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机译:用于鉴定导致测试样本感兴趣表型的突变的方法或系统
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摘要
A method for identifying mutations associated with the phenotype of interest in non vascular plants;(a) align the DNA sequence of the reference DNA sequenceIdentifying an array mismatch of the first set between two arrays;Test sampleDerived from mutated non vascular plantsIdentifying(b) the DNA sequence of at least one comparison sample is aligned with the reference DNA sequenceIdentifying an array mismatch of the second set between two arrays(c) with respect to the second set of mismatchesFilter the first set of mismatches andIdentifying a subset of mismatches that are specific to the first set mismatchIncludingMismatch subsetsIt is a candidate mutation of the cause mutation.Test sampleDerived from non vascular plants showing phenotypes of interestAt least one comparison sampleDerived from independent non vascular plants of the same genus that do not indicate the phenotypes of interest;Reference DNA sequencesIt is a known reference sequence of the non vascular plant of this genus.AndA method for identifying mutations associated with the phenotype of interest in non vascular plants;(a) align the DNA sequence of the reference DNA sequenceIdentifying an array mismatch of the first set between two arrays;Test sampleDerived from mutated non vascular plantsIdentifying(b) the DNA sequence of at least one comparison sample is aligned with the reference DNA sequenceIdentifying an array mismatch of the second set between two arrays(c) with respect to the array mismatch of the second setFilter the first set of mismatches andIdentifying a subset of mismatches common to the first and second set of array mismatchesIncludingTest samples and comparative samplesDerived from an independent non vascular plant showing the phenotype of interestIndependent non vascular plantsThe same genus;Reference DNA sequenceKnown reference sequences or non vascular plants of this genusIt is a non vascular plant of this genus.Diagram
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