TREATMENT AND PREVENTION OF NEISSERIA GONORRHOEAE INFECTION USING CMP-ACTIVATED NONULOSONATE ANALOG COMPOUNDS

摘要

A method for treating or preventing a Neisseria gonorrhoeae infection in a subject is provided. The method comprises administering to the subject an effective amount of a compound of general formula I below or a pharmaceutical composition comprising the compound. The compound is a cytidine 5′-monophospho-nonulosonate (CMP-NulO) analog compound, such as cytidine 5′-monophospho-3,7-dideoxy-7-azido-D-glycero-D-galacto-nonulosonic acid (CMP-KDN7N3).;