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Manufacturing method of exosomes for increasing their productivity and bioactivity and its application

机译:外泌体的制造方法,提高其生产率和生物活性及其应用

摘要

The present invention is a culture medium collected after culturing animal-derived cells in a serum-free medium to which platelet lysate is added and collecting the culture medium in the cell culture and culture medium recovery step for exosome production, not the step of proliferating the cells in the growth medium. It provides a method of producing exosomes for enhancing productivity and enhancing physiological activity, characterized in that the exosomes are separated from the exosomes.
机译:本发明是一种在培养动物衍生的细胞中收集的培养基,在添加血小板裂解物并在细胞培养和培养基回收步骤中收集培养基,以进行外部生产,而不是增殖的步骤 细胞在生长培养基中。 它提供了一种制备外泌体以提高生产率和增强生理活性的方法的方法,其特征在于外泌体与外泌体分离。

著录项

  • 公开/公告号KR20210157842A

    专利类型

  • 公开/公告日2021-12-29

    原文格式PDF

  • 申请/专利权人 주식회사 엑소코바이오;

    申请/专利号KR1020210004867

  • 发明设计人 조병성;하대현;

    申请日2021-01-13

  • 分类号C12N5/0775;A61K35/28;A61K8/98;A61P17/02;A61Q19;C12N5;

  • 国家 KR

  • 入库时间 2024-06-14 22:36:24

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