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Spirofused pyrrolidine derivatives as deubiquitinating enzyme (DUB) inhibitors

机译:螺旋形吡咯烷衍生物作为脱硫酶(配音)抑制剂

摘要

Problem to be solved: to provide a novel compound and a manufacturing method for the manufacture of an inhibitor of deubiquitinating enzyme (DUB).The present invention relates to a novel compound and a manufacturing method for the production of inhibitors of deubiquitinating enzymes (DUB). Specifically, the present invention relates to the inhibition of Cezanne 1. The invention further relates to the use of a dub inhibitor in the treatment of cancer.No selection
机译:要解决的问题:提供一种新化合物和制造脱氮酶(配合)抑制剂的制造方法。本发明涉及一种新型化合物和制造脱硫酶抑制剂(配音)的制造方法 。 具体地,本发明涉及Cezanne1的抑制1.本发明还涉及DUB抑制剂在治疗癌症中的使用。NO选择

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