PREPARATION AND USE OF ANTI-MET-AND-RON BISPECIFIC ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF

摘要

Provided herein are a preparation method and use of an anti-MET-and-RON bispecific antibody and an antibody-drug conjugate thereof. The anti-MET-and-RON bispecific antibody includes an anti-MET antibody fragment and an anti-RON antibody fragment which are linked to each other through a specific chemical “knobs-into-holes” structure.