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METHODS AND COMPOSITIONS FOR TREATMENT OF FRONTOTEMPORAL DEMENTIA
METHODS AND COMPOSITIONS FOR TREATMENT OF FRONTOTEMPORAL DEMENTIA
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机译:用于治疗终兆痴呆的方法和组合物
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摘要
Disclosed are methods and compositions for treating cognitive impairment due to frontotemporal dementia caused by progranulin mutations. More specifically, the invention relates to antisense oligonucleotides (ASOs) and their administration to subjects to increase progranulin protein levels in brain tissue, to treat cognitive impairment due to frontotemporal dementia caused by progranulin mutations.
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