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A CONTRAST AGENT FOR CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING, AND A CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING METHOD USING THE SAME
A CONTRAST AGENT FOR CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING, AND A CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING METHOD USING THE SAME
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机译:用于化学交换饱和传递磁共振成像的造影剂,以及使用相同的化学交换饱和传递磁共振成像方法
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摘要
The present invention relates to a contrast medium for saturation transition magnetic resonance imaging (CEST MRI) by chemical exchange and a method for saturation transition magnetic resonance imaging by chemical exchange using the same, wherein the contrast agent for CEST MRI is biguanide and derivatives thereof It includes any one compound selected from the group consisting of. The contrast agent for CEST MRI may image acidity by using CEST characteristics resulting from the chemical structure of the biguanide-based drug.
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机译:本发明涉及通过化学交换的饱和过渡磁共振成像(CEST MRI)的造影剂及其通过化学交换的饱和转变磁共振成像方法,其中用于CEST MRI的造影剂是双胍和其衍生物 包括选自组的任何一种化合物。 CEST MRI的造影剂可以通过使用由基于双胍的药物的化学结构产生的CEST特性来图像酸度。
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