METHOD FOR PREDICTING DEVELOPMENT OF SEVERE COVID-19 UTILIZING BLOOD RNA

摘要

The purpose of the present invention is to provide a method for predicting development of severe illness in patients infected with SARS-CoV-2. As a result of searching for markers for predicting development of severe illness in patients infected with SARS-CoV-2, the inventors discovered that illness subsequently tends to become severe in COVID-19 patients with high levels of miR-122-5p, SNORD33, AL732437.2, RNU2-29P, CDKN2B-AS1, let-7c-5p, miR-21-5p, miR-140-3p, and C5orf66-AS2 contained in their blood. Thus, the present invention provides a method for predicting development of severe illness in COVID-19 patients using these marker RNAs contained in blood exosomes.