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METHOD AND KIT FOR DISCRIMINATING BETWEEN PARKINSON'S DISEASE AND MULTIPLE SYSTEM ATROPHY

机译:用于区分帕金森病和多种系统萎缩的方法和套件

摘要

A method for discriminating between Parkinson's disease and multiple system atrophy, the method comprising the steps of: (1) preparing a solution containing α-synuclein monomers having a tendency to produce rod-like aggregates and/or a solution containing α-synuclein monomers having a tendency to produce twisted aggregates; (2) adding a biological sample from a subject to the solution (s) containing the α-synuclein monomers prepared in step (1); (3) allowing the α-synuclein monomers to aggregate in the solution(s) obtained in step (2); and (4) detecting α-synuclein aggregates formed in step (3).
机译:一种用于区分帕金森病和多系统萎缩的方法,该方法包括以下步骤:(1)制备含有α-突触核蛋白单体的溶液,其具有产生棒状聚集体和/或含有α-突触核蛋白单体的溶液的溶液 产生扭曲的聚集体的趋势; (2)从受试者中添加含有步骤(1)中制备的α-突触核蛋蛋白单体的溶液的生物样品; (3)允许α-突触核蛋白单体在步骤(2)中获得的溶液中聚集; (4)检测在步骤(3)中形成的α-突触核蛋白聚集体。

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