Single chewable tablet comprising montelukast and levocetirizine with improved stability and a process for the preparation thereof

摘要

The present invention relates to a single tablet containing montelukast and levocetirizine with improved stability and a method for preparing the same, and more particularly, to a pellet containing montelukast or a pharmaceutically acceptable salt thereof; And it relates to a single tablet in a mixed form comprising levocetirizine or a pharmaceutically acceptable salt thereof, and a method for preparing the same. In the single tablet according to the present invention, by applying montelukast pellets having an outer coating layer to the levocetirizine granules, the contact between the two drugs can be effectively blocked, improving stability and inhibiting the formation of related substances during long-term storage.