Application of the phosphodiesterase 4 inhibitor zl-n-91 in preparation of drugs for the treatment of prostate cancer proliferation and metastasis

摘要

The application of a new type of phosphodiesterase 4 (PED4) inhibitor ZL-n-91 in the preparation of a medicament for treating prostate cancer growth and metastasis is disclosed in the present invention. Animal and cell biology experiments in mice have shown that the phosphodiesterase 4 inhibitor ZL-n-91 of the present invention can significantly inhibit the growth and metastasis of prostate cancer cells, indicating that phosphodiesterase 4 inhibition Figure 2 shows that the agent ZL-n-91 is expected to be an important target for treating prostate cancer growth and metastasis. Provides the basis for the preparation of prostate cancer growth and metastasis inhibitors. The present invention provides a basis for the preparation of drugs for prostate cancer growth and metastasis with good prospects for development and application.