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CNT Densely aligned Carbon Nanotubes-based Biosensor for accurate sensing of Biomolecules and Use thereof

机译:CNT密集对准基于碳纳米管的生物传感器,用于精确感测生物分子和其用途

摘要

The present invention relates to a method for manufacturing a high-density aligned CNT-based biosensor for highly sensitive detection of biomolecules, a biosensor manufactured by the method, and uses thereof. Through the biosensor manufacturing method of the present invention, it is possible to manufacture a biosensor having the highest performance reported currently capable of detecting a target molecule present at a femtomolar level without cross-reactivity to a non-target molecule. In particular, it can accurately detect biomarkers present at a level of several femtomoles in a patient's sample, and it is accurate at low cost, out of the existing invasive or uneconomical time/monetary biomarker detection and diagnosis methods for neurodegenerative diseases. Detection and diagnosis of high biomarkers are possible. The biosensor manufacturing method and biosensor of the present invention are not only for neurodegenerative diseases, but also for diagnosis, prognosis, and probability prediction in various medical fields through high-accuracy detection of biomarkers that were difficult to detect due to low concentrations and presence of interfering substances. It can be usefully used, and in addition to medical purposes, it can be usefully used in various fields such as environment, food, military, industry, and research through detection of target molecules.
机译:本发明涉及一种用于制造高密度对准的基于CNT的生物传感器的方法,用于生物分子的高敏感性检测,由方法制造的生物传感器和其用途。通过本发明的生物传感器制造方法,可以制造具有目前能够检测在毫微微摩尔水平的靶分子而没有与非靶分子的交叉反应性的靶分子的生物传感器制造具有最高性能的生物传感器。特别地,它可以准确地检测患者样品中几个毫微微胶合水平的生物标志物,并且在现有的侵入性或不经济的时间/货币生物标志物检测和神经变性疾病的诊断方法中,它是准确的。对高生物标志物的检测和诊断是可能的。本发明的生物传感器制造方法和生物传感器不仅适用于神经变性疾病,而且对于各种医学领域的诊断,预后和概率预测,通过难以检测由于低浓度和存在而难以检测的生物标志物干涉物质。它可以是有用的,并且除了医学目的之外,它还可以用在环境,食品,军事,工业等各种领域中,通过检测目标分子。

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