Methods and Materials for Gender-Dependent Treatment of Cardiovascular Dysfunction

摘要

This document provides methods and materials for inclusion in the treatment of cardiovascular conditions, such as calcific aortic valve stenosis. Methods for using an sGC agonist or a combination of an sGC agonist and a PDE5A inhibitor, e.g., to reduce calcification of heart valves and/or blood vessels or to slow the progression from aortic sclerosis to calcific aortic valve stenosis and materials are provided.