USE OF A COMPOUND CONTAINING TWO OR MORE ALCOHOLIC HYDROXYL GROUPS OR PHENOLIC HYDROXYL GROUPS AS A MICROBIOME REGULATOR ON SCALP

摘要

Use of a compound containing two or more alcoholic hydroxyl groups or phenolic hydroxyl groups and three to sixteen carbon atoms per molecular, as microbiome regulator for selectively inhibiting Cutibacterium acnes and Staphylococcus epidermidis on scalp. A method of screening a compound or mixture for a microbiome regulator on scalp, comprising: testing Minimum Inhibitory Concentrations of the compound or mixture towards Cutibacterium acnes and Staphylococcus epidermidis, respectively; obtaining direct values of Minimum Inhibitory Concentration (Cutibacterium acnes) and Minimum Inhibitory Concentration (Staphylococcus epidermidis) of the compound or mixture, respectively; obtaining a calculated value of ( (Minimum Inhibitory Concentration (Cutibacterium acnes) /Minimum Inhibitory Concentration (Staphylococcus epidermidis) ) of the compound or mixture from the above direct values; and determining that the compound or mixture is suitable as a microbiome regulator on scalp, if the calculated value = 1. A shampoo or scalp serum composition, comprising a microbiome regulator for selectively inhibiting Cutibacterium acnes and Staphylococcus epidermidis on scalp, which is a compound containing two or more alcoholic hydroxyl groups or phenolic hydroxyl groups and three to sixteen carbon atoms per molecule, or the mixture thereof.