PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OBESITY OR NON-ALCOHOLIC FATTY LIVER COMPRISING DENTAL TISSUE-DERIVED MESENCHYMAL STEM CELLS

摘要

The present invention relates to a pharmaceutical composition for preventing or treating obesity or non-alcoholic fatty liver, comprising mesenchymal stem cells derived from super magnetized and cryopreserved tooth surrounding tissues. The pharmaceutical composition for the prevention or treatment of obesity or nonalcoholic fatty liver of the present invention significantly prevents obesity or nonalcoholic fatty liver by reducing body weight, decreasing serum adipokine concentration, recovering histological findings of the liver, and improving lipid metabolizing enzymes in the liver and therapeutic effects. In addition, the mesenchymal stem cells derived from peripheral tissues of the present invention, which are mesenchymal stem cells with proven safety, can be obtained by the most non-invasive method, and are useful as a cell therapeutic agent for obesity or non-alcoholic fatty liver. expected to be used.