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Metal / radiometal labeled PSMA inhibitors for imaging and radiation therapy targeting PSMA
Metal / radiometal labeled PSMA inhibitors for imaging and radiation therapy targeting PSMA
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机译:金属/辐射截止物标记的PSMA抑制剂,用于成像和放射治疗靶向PSMA
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摘要
Low-molecular weight gadolinium (Gd)-based MR contrast agents for PSMA-specific Ti-weighted MR imaging are disclosed. The (Gd)-based MR contrast agents exhibit high binding affinity for PSMA and exhibit specific Tcontrast enhancement at PSMA+ cells. The PSMA-targeted Gd-based MR contrast agents can be used for PSMA-targeted imagingY-labeled PSMA-binding ureas also are provided, wherein the PSMA-binding ureas also are suitable for use with other radiotherapeutics.
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