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Techniques for rapid detection and quantification of volatile organic compounds (VOCs) using exhaled breath samples

机译:使用呼出的呼吸样品快速检测和定量挥发性有机化合物(VOC)的技术

摘要

An exemplary breath analysis system can include a sampling chamber in which a molecular collector is located. The molecular detector may be configured such that the volatile organic compounds (VOCs) present in the exhaled sample introduced into the sampling chamber adhere to the molecular collector. The heating element can introduce heat into the sampling chamber and result in the release of at least a portion of the VOC attached to the molecular collector. Analytical devices (eg, mass spectrometers or terahertz (THz) spectrometers) identify one or more target VOCs from at least a portion of the VOCs emitted from the molecular collector and one or more identified. An output representing the target VOC may be generated. The output may include information that quantifies the concentration of one or more target VOCs relative to the source of the exhaled sample. [Selection diagram] Fig. 1
机译:示例性呼气分析系统可包括其中分子收集器所在的采样室。 分子检测器可以配置成使得存在于将进入采样室中的呼出样品中的挥发性有机化合物(VOC)粘附在分子收集器中。 加热元件可以将热量引入取样室,并导致释放附着在分子收集器上的VOC的至少一部分。 分析装置(例如,质谱仪或Terahertz(Thz)光谱仪)从来自分子收集器发射的VOC的至少一部分和一个或多个鉴定的识别一个或多个目标VOC。 可以生成表示目标VOC的输出。 输出可以包括相对于呼出样品的来源来定量一个或多个目标VOC浓度的信息。 [选择图]图1

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