SET OF OLIGONUCLEOTIDE PRIMERS AND FLUORESCENTLY LABELLED PROBES FOR IDENTIFYING THE EPIGENETIC MARKERS OF CERVICAL CANCER

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to the field of medical biotechnology. In order to solve the posed problem, methylated RCGY sites of the promoter areas of the tumour marker genes CADM1, MAL, PAX1, DAPK1, FAM19A4, PRDM14 are determined using the GLAD-PCR method, and specially developed oligonucleotide primers and probes are used to determine these sections.;EFFECT: creation of a set of oligonucleotide primers and fluorescently labelled probes for determining the level of methylation of epigenetic markers causing the occurrence of cervical cancer by the GLAD-PCR method.;1 cl, 3 tbl, 1 dwg