The present invention relates to a composition for the prevention, improvement and treatment of blood cancer comprising a compound derived from yangjegeun extract as an active ingredient, which is derived from yangjegeun, a natural product, which is safe for the human body, has a strong mitochondrial depolarization effect, and increases the level of reactive oxygen species It can be used for the prevention or treatment of hematologic cancer because it exhibits apoptosis-inducing activity in leukemia cells by delaying the cell cycle progression and increasing the number of apoptotic cells.
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