Composition for Anti-Inflammation or Anti-Diabetes Comprising Metabolites From a Marine-Derived Fungal Strain Penicillium glabrum SF-7123

摘要

The present invention relates to a pharmaceutical composition for anti-inflammatory or anti-diabetes containing a metabolite of the marine-derived fungus Penicillium glabrum SF-7123, a food for improving inflammation or diabetes, and a method for isolating the metabolite. The composition comprising the metabolite of the marine-derived fungus Penicillium glabrum SF-7123 according to the present invention is NO, prostaglandin E 2 (PGE 2 ), inducible nitric oxide enzyme (iNOS) and cyclooxygenase Since it inhibits the production of pro-inflammatory mediators such as -2 (COX-2) and the expression of PTP1B, it can be usefully used for the prevention or treatment of inflammatory diseases or diabetes.