Vaccine compositions and methods for reducing transmission to Streptococcus pneumoniae

摘要

S. that is necessary for or involved in bacterial transmission between mammalian hosts. Mammalian transmission of Streptococcus pneumoniae (S. pneumoniae) by administering to a mammalian subject a vaccine composition comprising at least one immunogenic polypeptide comprising a pneumoniae protein or fragment or variant thereof Compositions and methods are provided for reducing. These vaccine compositions also contain S. It serves to reduce the incidence of at least one invasive disease caused by pneumonia. s. Methods of identifying additional genetic factors involved in mammalian transmission of pneumonia are also provided.