首页> 外国专利> REDUCTION OF CYTOKINE STORM AND PATHOLOGICAL INFLAMMATION INCLUDING CAUSED BY CORONAVIRUS USING SPHAGNUM AND EXTRACTS THEREOF

REDUCTION OF CYTOKINE STORM AND PATHOLOGICAL INFLAMMATION INCLUDING CAUSED BY CORONAVIRUS USING SPHAGNUM AND EXTRACTS THEREOF

机译:减少细胞因子风暴和病理炎症,包括使用SpHagnum和提取物引起的冠状病毒引起的

摘要

Disclosed are treatments, compositions of matter, and protocols for reducing, ameliorating, or reversing excess inflammation and/or cytokine storm through administration of Sphagnum and/or extracts thereof. In particular embodiments, a patient at risk for cytokine storm is administered a Sphagnum extract at a concentration sufficient to induce an immunomodulatory change in said patient, including suppression of macrophage activation, reduction of neutrophil activation and inhibition of DNA extracellular trap release. In some embodiments, Sphagnum, or extracts thereof are administered together with other agents to enhance activity in treatment of Covid-19 infection and associated pathologies. In some embodiments, humic acid and/or analogues thereof are administered for reduction of pathological inflammation and/or stimulation of immunity.
机译:公开了通过施用SpHagnum和/或提取物来减少,改善或逆转过量炎症和/或细胞因子风暴的处理,物质组合物和方案。 在特定实施方案中,患有细胞因子风险的患者以足以诱导所述患者的免疫调节变化的浓度给药,包括抑制巨噬细胞活化,降低中性粒细胞活化和抑制DNA细胞外捕集释放。 在一些实施方案中,与其他试剂一起施用sphagnum或提取物,以增强治疗Covid-19感染和相关病理的活性。 在一些实施方案中,施用腐殖酸和/或其类似物以降低病理炎症和/或刺激免疫。

著录项

  • 公开/公告号WO2021226627A1

    专利类型

  • 公开/公告日2021-11-11

    原文格式PDF

  • 申请/专利权人 FIGENE LLC;

    申请/专利号WO2021US70504

  • 发明设计人 OHEERON PETE;ICHIM THOMAS;

    申请日2021-05-04

  • 分类号A01G22;A01G22/30;A61K36;

  • 国家 US

  • 入库时间 2022-08-24 22:29:14

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