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COMBINATIONS OF DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS AND ACETYL-COA CARBOXYLASE INHIBITOR

机译:二氨基甘油酰基转移酶2抑制剂和乙酰-CoA羧化酶抑制剂的组合

摘要

Described herein are pharmaceutical compositions comprising 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide, or pharmaceutically acceptable salt thereof, for treatment of liver disease and diseases related thereto. Also described are compositions comprising 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-5 carboxamide, or pharmaceutically acceptable salt thereof and 4-(4-(1-Isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid, or pharmaceutically acceptable salt thereof, for treatment of liver disease and diseases related thereto.
机译:本文所述的药物组合物是包含2- {5- [(3-乙醇型-2-基)氧]吡啶-3-Y1} -N-[(3S,5S)-5-氟哌啶-3-基]嘧啶-5的药物组合物 -Carboblamide或其药学上可接受的盐,用于治疗肝病和疾病。 还描述了包含2- {5 - [(3-乙醇吡啶-2-基)氧]吡啶-3-Y1} -N-[(3S,5S)-5-氟哌啶-3-基]嘧啶-5-的组合物。嘧啶-5- 5甲酰胺,或其药学上可接受的盐和4-(4-(4-(1-异丙基-7-氧代-1,4,6,7-四氢氟化氢硼(4-四氢)-6 - 甲氧基吡啶-2-基)苯甲酸,或其药学上可接受的盐,用于治疗肝病和与其相关的疾病。

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