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TREATMENT AND PLANNING FOR LYMPHOCYTES SPARING RADIOTHERAPY

机译:淋巴细胞抑制放疗的治疗和规划

摘要

The present document relates to providing a radiation treatment plan for treatment of a neoplasm, including the steps of: obtaining an image including the neoplasm and obtaining first segmentation data for segmenting at least one target- volume to be targeted with radiation. Further identifying any organs-at-risk and segmenting these. The method further comprises identifying lymphocyte-rich-organs in the image, and obtaining third segmentation data for segmenting the lymphocyte- rich-organs. The planning system then obtains radiation dose regime data, including first, second and third dose regime data. The planning system then determines a radiation treatment plan which provides treatment process parameters for operating one or more radiation beams for radiation treatment of the neoplasm, The process parameters are determined to apply the radiation at a first radiation dose to the target volume which corresponds with the first dose regime data, apply the radiation at a minimized second radiation dose to the or each organs-at-risk, and apply the radiation at a third radiation dose to the or each lymphocyte-rich-organ which corresponds with the third dose regime data, wherein the third radiation dose amount is minimized.
机译:本文献涉及提供用于治疗肿瘤的放射治疗计划,包括以下步骤:获得包括肿瘤的图像并获得用于分割至少一种靶体积的第一分段数据以靶向辐射。进一步识别任何机构风险和细分这些。该方法还包括在图像中鉴定富含淋巴细胞的器官,并获得用于分割含淋巴细胞 - 富噬菌体的第三分段数据。然后,规划系统获得辐射剂量制度数据,包括第一,第二和第三剂量制度数据。然后,规划系统确定提供用于操作一个或多个辐射束的处理过程参数的辐射处理计划,用于对肿瘤进行辐射处理,确定工艺参数以将第一辐射剂量的辐射施加到目标体积上对应于第一剂量制度数据,将辐射施加到最小化的第二辐射剂量到或每个器官 - 风险,并将第三辐射剂量的辐射施加到或每个富含淋巴细胞的器官,其对应于第三剂量制度数据,其中第三辐射剂量最小化。

著录项

  • 公开/公告号WO2021172991A1

    专利类型

  • 公开/公告日2021-09-02

    原文格式PDF

  • 申请/专利权人 UNIVERSITEIT MAASTRICHT;

    申请/专利号WO2021NL50129

  • 发明设计人 LAMBIN PHILIPPE;DUBOIS LUDWIG JEROME;

    申请日2021-02-26

  • 分类号A61N5/10;

  • 国家 NL

  • 入库时间 2022-08-24 22:25:28

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