A NOVEL SYNTHETIC ROUTE FOR THE PRODUCTION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE AND THIAZOLE DERIVATE

摘要

It relates to a method for preparing an intermediate for the preparation of edoxaban, which is an optically active diamine derivative (compound 7) and thiazole derivative (compound 10), which are intermediates of edoxaban, without the use of high-pressure equipment and metal catalysts, with high yield and purity It relates to a method for producing an intermediate for the production of edoxaban that can be obtained as