Pharmaceutical composition for prevention or treatment inflammatory diseases comprising comprising root extract Hovenia dulcis or fractions thereof or compounds isolated from therefrom

摘要

The present invention relates to a composition for the prevention or treatment of inflammatory diseases comprising, as an active ingredient, an extract of the rhododendron tree root, a fraction thereof, or a compound isolated therefrom, and specifically, the extract, a fraction thereof, or a compound isolated therefrom. It relates to a pharmaceutical composition for prevention or treatment, and a food composition for prevention or improvement, including. Since the extract of Heotgae tree root of the present invention, a fraction thereof, and a compound isolated therefrom inhibit the production of inflammatory cytokines, prostaglandin E2, and nitric oxide, which are inflammatory mediators, they can be usefully used for the prevention, treatment or improvement of inflammatory diseases. In addition, since the root extract, fractions thereof, and compounds isolated therefrom of the present invention are derived from natural products, they can be safely used for preventing or treating and improving inflammatory diseases without side effects.