Chimeric antigen receptor specific for G protein-coupled receptor C class 5 group D member (GPD)

摘要

Provided is a chimeric antigen receptor (CAR) containing an antibody portion specific for a G protein coupled receptor C class 5 group D member (GPRC5D) and a polynucleotide encoding a CAR specific for GPRC5D. The present disclosure also relates to genetically engineered cells containing said GPRC5D-coupled receptors and their use in adoptive cell therapy.