首页> 外国专利> A cell composition comprising retinal cell having characteristics of photoreceptor cells and retinal pigment epithelial cell simultaneously and use thereof

A cell composition comprising retinal cell having characteristics of photoreceptor cells and retinal pigment epithelial cell simultaneously and use thereof

机译:一种细胞组合物,其包含视网膜细胞,同时具有光感受细胞和视网膜颜料上皮细胞的特性和用途

摘要

The present invention relates to a cell composition comprising retinal cells exhibiting the characteristics of photoreceptor cells and retinal pigment epithelial cells at the same time and uses thereof, and more particularly, to human pluripotent stem cells by treatment with a ROCK inhibitor at a constant concentration for a certain period of time. Cell composition containing retinal cells differentiated from (embryonic stem cells or dedifferentiated stem cells) and simultaneously exhibiting the characteristics of photoreceptor cells and retinal pigment epithelial cells, cell therapy for preventing or treating retinal diseases, including photoreceptors The present invention relates to a method for producing retinal cells simultaneously exhibiting the characteristics of cells and retinal pigment epithelial cells, and to a differentiation composition for differentiating into retinal cells simultaneously exhibiting the characteristics of photoreceptor cells and retinal pigment epithelial cells.
机译:本发明涉及一种细胞组合物,其包含视网膜细胞,其同时使用具有光感受细胞和视网膜色素上皮细胞的特性,更具体地,通过用恒定浓度的岩石抑制剂处理来处理人多能干细胞一段时间。含有视网膜细胞的细胞组合物分化为(胚胎干细胞或去分化的干细胞),同时表现出感光细胞和视网膜颜料上皮细胞的特征,用于预防或治疗视网膜疾病的细胞疗法,包括光感受器本发明涉及一种生产方法视网膜细胞同时表现出细胞和视网膜颜料上皮细胞的特征,以及分化成视网膜细胞的分化组合物,同时表现出感光细胞和视网膜色素上皮细胞的特征。

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