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SYSTEM FOR SIMULATING MOLECULAR INTERACTIONS INVOLVED IN INFLAMMATION
SYSTEM FOR SIMULATING MOLECULAR INTERACTIONS INVOLVED IN INFLAMMATION
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机译:模拟炎症中涉及的分子相互作用的系统
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摘要
The present invention relates to the filed of simulation of molecular interactions for assessing diseases and disease therapies. In particular, it relates to a system for simulating molecular interactions involved in inflammation in a subject, said system comprising a processing unit comprising a database comprising a plurality of datasets each comprising at least an identifier for a molecule suspected to be involved in the pathological process, data on molecular interactions of the said molecule with one or more other molecule, and at least one data characteristic that is allocated to the dataset, wherein each dataset has at least one relation with another dataset in the database based on molecular interactions, wherein the datasets are grouped into data compartments comprising datasets having identical data characteristics, and wherein the data characteristics are indicative for the biological function of a molecule in inflammation, and an computer program-based algorithm implemented in the processing unit which generates a network map based on the plurality of datasets in the database and which allows for identifying nodes within network map based on predefined parameters, and a visualization unit which allows for determination of the molecular interactions in the identified nodes. Moreover, the present invention contemplates a method for simulating molecular interactions involved in inflammation in a subject as well as the use of the system of the invention for simulating molecular interactions involved in inflammation.
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