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Multilayer thin film drug delivery device and methods of making and using the same

机译:多层薄膜药物递送装置和制造方法和使用方法

摘要

Multilayer thin film devices that include a bioactive agent for elution to the surrounding tissue upon administration to a subject are provided. The multilayer thin film devices are useful as medical devices, such as ocular devices. Also provided are methods and kits for localized delivery of a bioactive agent to a tissue of a subject, and methods of preparing the subject devices. The multilayer thin film medical device includes a first layer, a bioactive agent and a second layer. The first and the second layers may be porous or non-porous. The devices have a furled structure, suitable for administration to a subject.
机译:提供了包括用于在给予受试者时向周围组织洗脱的生物活性剂的多层薄膜装置。 多层薄膜装置可用作医疗装置,例如眼器件。 还提供了用于将生物活性剂的局部递送至受试者的组织的方法和试剂盒,以及制备主体装置的方法。 多层薄膜医疗装置包括第一层,生物活性剂和第二层。 第一层和第二层可以是多孔的或非多孔的。 该装置具有毛细的结构,适合于给予受试者。

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